Title : Deoxynivalenol Induces Inflammation in IPEC-J2 Cells by Activating P38 Mapk And Erk1/2.

Pub. Date : 2020 Mar 13

PMID : 32183221






2 Functional Relationships(s)
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Protein Name
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1 DON increased IL1A, IL6 and TNF-alpha release and DON activated the phosphorylation of extracellular signal-regulated kinase-1 and-2 (ERK1/2), JUN N-terminal kinase (JNK) and p38 MAPK. deoxynivalenol interleukin 1 alpha Sus scrofa
2 A p38 inhibitor attenuated DON-induced IL6, TNF-alpha, CXCL2, CXCL8, IL12A, IL1A, CCL20, CCL4 and IL15 production, while an ERK1/2 inhibitor had only a small inhibitory effect on IL15 and IL6. deoxynivalenol interleukin 1 alpha Sus scrofa