Pub. Date : 2020 Mar 13
PMID : 32183221
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | DON increased IL1A, IL6 and TNF-alpha release and DON activated the phosphorylation of extracellular signal-regulated kinase-1 and-2 (ERK1/2), JUN N-terminal kinase (JNK) and p38 MAPK. | deoxynivalenol | interleukin 1 alpha | Sus scrofa |
2 | A p38 inhibitor attenuated DON-induced IL6, TNF-alpha, CXCL2, CXCL8, IL12A, IL1A, CCL20, CCL4 and IL15 production, while an ERK1/2 inhibitor had only a small inhibitory effect on IL15 and IL6. | deoxynivalenol | interleukin 1 alpha | Sus scrofa |