Title : Activity of Imipenem-Relebactam against Carbapenem-Resistant Escherichia coli Isolates from the United States in Relation to Clonal Background, Resistance Genes, Coresistance, and Region.

Pub. Date : 2020 Apr 21

PMID : 32152073






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1 Imipenem/relebactam (I/R) is a recently developed carbapenem/beta-lactamase inhibitor combination agent that can overcome carbapenem resistance, which has now emerged in Escherichia coli, including sequence type 131 (ST131) and its fluoroquinolone-resistant H30R subclone, the leading cause of extra-intestinal E. coli infections globally. Carbapenems beta-lactamase Escherichia coli