Title : Evaluation of cisplatin-induced injury in human kidney organoids.

Pub. Date : 2020 Apr 1

PMID : 32150447






2 Functional Relationships(s)
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1 We found that a single treatment with 50 microM cisplatin induces hepatitis A virus cellular receptor 1 (HAVCR1) and C-X-C motif chemokine ligand 8 (CXCL8) expression, DNA damage (gammaH2AX), and cell death in the organoids but greatly impairs organoid viability. Cisplatin C-X-C motif chemokine ligand 8 Homo sapiens
2 We found that a single treatment with 50 microM cisplatin induces hepatitis A virus cellular receptor 1 (HAVCR1) and C-X-C motif chemokine ligand 8 (CXCL8) expression, DNA damage (gammaH2AX), and cell death in the organoids but greatly impairs organoid viability. Cisplatin C-X-C motif chemokine ligand 8 Homo sapiens