Pub. Date : 2020 Mar 6
PMID : 32143662
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Variants in RETN gene are associated with steroid-induced osteonecrosis of the femoral head risk among Han Chinese people. | Steroids | resistin | Homo sapiens |
| 2 | Moreover, steroid-induced osteonecrosis of the femoral head (steroid-induced ONFH) is closely related to lipid metabolism level, so this study is intended to explore the relationship of RETN polymorphisms with susceptibility to steroid-induced ONFH in the Chinese Han population. | Steroids | resistin | Homo sapiens |
| 3 | Moreover, steroid-induced osteonecrosis of the femoral head (steroid-induced ONFH) is closely related to lipid metabolism level, so this study is intended to explore the relationship of RETN polymorphisms with susceptibility to steroid-induced ONFH in the Chinese Han population. | Steroids | resistin | Homo sapiens |
| 4 | Moreover, steroid-induced osteonecrosis of the femoral head (steroid-induced ONFH) is closely related to lipid metabolism level, so this study is intended to explore the relationship of RETN polymorphisms with susceptibility to steroid-induced ONFH in the Chinese Han population. | Steroids | resistin | Homo sapiens |
| 5 | METHODS: In this case-control study, eight single-nucleotide polymorphisms (SNPs) of RETN were genotyped by the Agena MassARRAY system in 199 steroid-induced ONFH patients and 200 healthy controls. | Steroids | resistin | Homo sapiens |
| 6 | The relationship between RETN polymorphisms and steroid-induced ONFH risk was assessed using genetic models and haplotype analyses. | Steroids | resistin | Homo sapiens |
| 7 | CONCLUSIONS: Our results provide the firstly evidence that RETN gene polymorphisms were associated with a reduced risk of steroid-induced ONFH in Chinese Han population. | Steroids | resistin | Homo sapiens |