Title : Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes.

Pub. Date : 2020 Mar

PMID : 32143184






1 Functional Relationships(s)
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1 In this context, the ectopic recovery of miR-30b and miR-30c led to significant changes in genes related to FA metabolism, consistent reduction of ceramides, higher mitochondrial activity, and enabled beta-oxidation, redirecting FA metabolism from energy storage to expenditure. Ceramides microRNA 30c-1 Homo sapiens