Title : Poly(I:C) augments inactivated influenza virus-chitosan nanovaccine induced cell mediated immune response in pigs vaccinated intranasally.

Pub. Date : 2020 Mar

PMID : 32122615






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1 In addition, the chitosan nanovaccine induced the proliferation of antigen-specific IFNgamma secreting T-helper/memory and gammadelta T cells compared to control poly(I:C) group; and an increased Th1 (IFNgamma, IL-6 and IL-2) and Th2 (IL-10 and IL-13) cytokines mRNA expression in the tracheobronchial lymph nodes compared to lymphoid tissues obtained from pigs given commercial influenza vaccine. nanovaccine interleukin 13 Sus scrofa