Title : Hepatic monoamine oxidase B is involved in endogenous geranylgeranoic acid synthesis in mammalian liver cells.

Pub. Date : 2020 May

PMID : 32094232






2 Functional Relationships(s)
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1 Using either HuH-7 cell lysates or recombinant human MAOB, we found (i) that the MAO inhibitor tranylcypromine dose-dependently down-regulates endogenous GGA levels in HuH-7 cells, and (ii) that siRNA-mediated MAOB silencing reduces intracellular GGA levels in HuH-7 and Hep3B cells. Tranylcypromine monoamine oxidase B Homo sapiens
2 Using either HuH-7 cell lysates or recombinant human MAOB, we found (i) that the MAO inhibitor tranylcypromine dose-dependently down-regulates endogenous GGA levels in HuH-7 cells, and (ii) that siRNA-mediated MAOB silencing reduces intracellular GGA levels in HuH-7 and Hep3B cells. Tranylcypromine monoamine oxidase B Homo sapiens