Title : Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice.

Pub. Date : 2020 Apr

PMID : 32087947






1 Functional Relationships(s)
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1 We investigated the impact of reduced sialylation in the brain of mice heterozygous for the enzyme glucosamine-2-epimerase/N-acetylmannosamine kinase (GNE+/-) that is essential for sialic acid biosynthesis. N-Acetylneuraminic Acid glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Mus musculus