Title : Potent Inhibition of Thioredoxin Reductase by the Rh Derivatives of Anticancer M(arene/Cp*)(NHC)Cl2 Complexes.

Pub. Date : 2020 Mar 2

PMID : 32073260






1 Functional Relationships(s)
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1 In an attempt to tie the localization of the compounds to the inhibition of the tentative target TrxR, it was surprisingly found that only the Rh complexes showed significant inhibitory activity at IC50 values of ~1 muM, independent of the substituents on the NHC ligand. Rhodium latexin Homo sapiens