Title : Anionic versus neutral Pt(II) complexes: The relevance of the charge for human serum albumin binding.

Pub. Date : 2020 May

PMID : 32070915






2 Functional Relationships(s)
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1 Anionic versus neutral Pt(II) complexes: The relevance of the charge for human serum albumin binding. Platinum albumin Homo sapiens
2 The focus of this work is pointing out the different behavior of two structurally related Pt(II) complexes, the anionic cyclometalated NBu4[(Bzq)Pt(Thio)], 1 and the neutral [(Phen)Pt(Thio)], 2, (Bzq = benzo[h]quinoline, Phen = 1,10-phenantroline, Thio = 1,2-benzenedithiolate), on the interaction with human serum albumin (HSA), a key drug-delivery protein in the bloodstream. Platinum albumin Homo sapiens