Title : PI3K-Akt-mTOR/PFKFB3 pathway mediated lung fibroblast aerobic glycolysis and collagen synthesis in lipopolysaccharide-induced pulmonary fibrosis.

Pub. Date : 2020 Jun

PMID : 32051533






2 Functional Relationships(s)
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1 In addition, PFKFB3 expression and aerobic glycolysis were also detected in the mouse model of LPS-induced pulmonary fibrosis, which could be reversed by the intraperitoneal injection of PFKFB3 inhibitor 3PO. 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Mus musculus
2 In addition, PFKFB3 expression and aerobic glycolysis were also detected in the mouse model of LPS-induced pulmonary fibrosis, which could be reversed by the intraperitoneal injection of PFKFB3 inhibitor 3PO. 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Mus musculus