Title : Differential expression of genes associated with T lymphocytes function in septic patients with hypoxemia challenge.

Pub. Date : 2019 Dec

PMID : 32042826






1 Functional Relationships(s)
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1 Candidate genes were identified after adjustment for age, sex and presence of lymphopenia with significantly negative correlations with partial pressure of O2 in an arterial blood (PaO2) and fraction of inspiration O2 (FiO2) ratio, among which NLRP3, SOS1, ELF1 and STAT3 held an increasing expression in ex vivo validation while the others, PSMA5, CLEC4D, CD300A, PRKD2 and PSMA2 showed the opposite alteration from those in vivo. fio2 C-type lectin domain family 4 member D Homo sapiens