Pub. Date : 2020 Apr
PMID : 32041439
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Binding mode of sulforaphane within caspase-1 was determined by molecular docking simulation. | sulforaphane | caspase 1 | Homo sapiens |
| 2 | In the molecular docking simulation and in vitro caspase-1 assays, sulforaphane regulated caspase-1 activity by docking with the identical binding site of caspase-1. | sulforaphane | caspase 1 | Homo sapiens |
| 3 | In the molecular docking simulation and in vitro caspase-1 assays, sulforaphane regulated caspase-1 activity by docking with the identical binding site of caspase-1. | sulforaphane | caspase 1 | Homo sapiens |
| 4 | In the molecular docking simulation and in vitro caspase-1 assays, sulforaphane regulated caspase-1 activity by docking with the identical binding site of caspase-1. | sulforaphane | caspase 1 | Homo sapiens |
| 5 | Furthermore, phosphorylation of mitogen-activated protein kinases (MAPK) was down-regulated by treatment with sulforaphane or WE.Conclusion: Our findings suggest that sulforaphane and WE have anti-allergic inflammatory effects by intercepting caspase-1/NF-kappaB/MAPKs signaling pathways. | sulforaphane | caspase 1 | Homo sapiens |
| 6 | Furthermore, phosphorylation of mitogen-activated protein kinases (MAPK) was down-regulated by treatment with sulforaphane or WE.Conclusion: Our findings suggest that sulforaphane and WE have anti-allergic inflammatory effects by intercepting caspase-1/NF-kappaB/MAPKs signaling pathways. | sulforaphane | caspase 1 | Homo sapiens |