Title : Radiation activates myeloperoxidase (MPO) to generate active chlorine species (ACS) via a dephosphorylation mechanism - inhibitory effect of LGM2605.

Pub. Date : 2020 Jul

PMID : 32035161






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 METHODS: MPO-dependent ACS generation was determined by using hypochlorite-specific 3"-(p-aminophenyl) fluorescein (APF) and a highly potent MPO inhibitor, 4-aminobenzoic acid hydrazide (ABAH), and confirmed in PMN derived from MPO-/- mice. 4-aminobenzhydrazide myeloperoxidase Mus musculus
2 METHODS: MPO-dependent ACS generation was determined by using hypochlorite-specific 3"-(p-aminophenyl) fluorescein (APF) and a highly potent MPO inhibitor, 4-aminobenzoic acid hydrazide (ABAH), and confirmed in PMN derived from MPO-/- mice. 4-aminobenzhydrazide myeloperoxidase Mus musculus
3 METHODS: MPO-dependent ACS generation was determined by using hypochlorite-specific 3"-(p-aminophenyl) fluorescein (APF) and a highly potent MPO inhibitor, 4-aminobenzoic acid hydrazide (ABAH), and confirmed in PMN derived from MPO-/- mice. 4-aminobenzhydrazide myeloperoxidase Mus musculus
4 METHODS: MPO-dependent ACS generation was determined by using hypochlorite-specific 3"-(p-aminophenyl) fluorescein (APF) and a highly potent MPO inhibitor, 4-aminobenzoic acid hydrazide (ABAH), and confirmed in PMN derived from MPO-/- mice. 4-aminobenzhydrazide myeloperoxidase Mus musculus