Title : Synthesis and biological evaluation of pyrazolone analogues as potential anti-inflammatory agents targeting cyclooxygenases and 5-lipoxygenase.

Pub. Date : 2020 Apr

PMID : 32031284






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 New pyrazolone derivatives structurally related to celecoxib and FPL 62064 were synthesized and biologically evaluated for their inhibitory activity against cyclooxygenases (COXs) and 5-lipoxygenase (5-LOX) and their selectivity indices were calculated. celecoxib arachidonate 5-lipoxygenase Rattus norvegicus