Title : HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation.

Pub. Date : 2020 Mar

PMID : 32028527






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 These post-translational modification events are predominantly serine-linked and require HPF1, an accessory factor that is specific for the DNA damage response and switches the amino-acid specificity of PARP1/2 from aspartate/glutamate to serine residues5-10. Aspartic Acid histone PARylation factor 1 Homo sapiens