Title : Synthetic analogues of 2-oxo acids discriminate metabolic contribution of the 2-oxoglutarate and 2-oxoadipate dehydrogenases in mammalian cells and tissues.

Pub. Date : 2020 Feb 5

PMID : 32024885






2 Functional Relationships(s)
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Protein Name
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1 The saccharopine pathway intermediates and phosphorylated sugars are abundant when cellular expressions of DHTKD1 and OGDH are comparable, while nicotinate and non-phosphorylated sugars are when DHTKD1 expression is order(s) of magnitude lower than that of OGDH. Carbohydrates dehydrogenase E1 and transketolase domain containing 1 Homo sapiens
2 The saccharopine pathway intermediates and phosphorylated sugars are abundant when cellular expressions of DHTKD1 and OGDH are comparable, while nicotinate and non-phosphorylated sugars are when DHTKD1 expression is order(s) of magnitude lower than that of OGDH. Carbohydrates dehydrogenase E1 and transketolase domain containing 1 Homo sapiens