Pub. Date : 2020 Jan 30
PMID : 32019062
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Downregulation of Astrocytic Kir4.1 Potassium Channels Is Associated with Hippocampal Neuronal Hyperexcitability in Type 2 Diabetic Mice. | Potassium | potassium inwardly-rectifying channel, subfamily J, member 10 | Mus musculus |
| 2 | Hyperglycemia downregulates inwardly rectifying potassium channel 4.1 (Kir4.1) in cultured astrocytes. | Potassium | potassium inwardly-rectifying channel, subfamily J, member 10 | Mus musculus |
| 3 | In diabetic mice, astrocytic Kir4.1 channels were functionally downregulated as evidenced by multiple characteristics including depolarized membrane potential, reduced barium-sensitive Kir currents and impaired potassium uptake capabilities of hippocampal astrocytes. | Potassium | potassium inwardly-rectifying channel, subfamily J, member 10 | Mus musculus |