Title : Stabilizing cardiac ryanodine receptor prevents the development of cardiac dysfunction and lethal arrhythmia in Ca2+/calmodulin-dependent protein kinase IIδc transgenic mice.

Pub. Date : 2020 Apr 2

PMID : 32007269






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In the chronic DAN-treated cardiomyocytes, CS increased, sCaTs decreased, and the endogenous CaM binding to RyR2 normally restored. Dantrolene ryanodine receptor 2 Homo sapiens
2 The phosphorylation levels of Ser2814 in RyR2 and Thr287 in CaMKII remained elevated even after DAN treatment. Dantrolene ryanodine receptor 2 Homo sapiens