Pub. Date : 1988
PMID : 3199460
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) caused a dose-dependent decrease of adipose tissue lipoprotein lipase (LPL) activity and caused a concomitant increase in serum triglyceride concentration in the rabbit 10 d after single ip administration of either 1 or 50 micrograms/kg. | Polychlorinated Dibenzodioxins | lipoprotein lipase | Oryctolagus cuniculus |
| 2 | TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) caused a dose-dependent decrease of adipose tissue lipoprotein lipase (LPL) activity and caused a concomitant increase in serum triglyceride concentration in the rabbit 10 d after single ip administration of either 1 or 50 micrograms/kg. | Polychlorinated Dibenzodioxins | lipoprotein lipase | Oryctolagus cuniculus |
| 3 | It is proposed that TCDD causes hyperlipidemia in the rabbit through suppression of LPL activity and LDL receptor binding. | Polychlorinated Dibenzodioxins | lipoprotein lipase | Oryctolagus cuniculus |