Title : Embelin averts MPTP-induced dysfunction in mitochondrial bioenergetics and biogenesis via activation of SIRT1.

Pub. Date : 2020 Mar 1

PMID : 31987812






1 Functional Relationships(s)
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1 The mitochondrial uncoupling effects of embelin leading to increased NAD/NADH levels followed by enhanced SIRT1, PGC1alpha and mitochondrial biogenesis were found to confer embelin mediated protection as treatment of cells with SIRT1 inhibitor or siRNA nullified this effect. NAD sirtuin 1 Mus musculus