Title : LYW-6, a novel cryptotanshinone derived STAT3 targeting inhibitor, suppresses colorectal cancer growth and metastasis.

Pub. Date : 2020 Mar

PMID : 31982491






1 Functional Relationships(s)
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1 Western blot analysis and electrophoretic mobility shift assays (EMSA) showed that LYW-6 inhibited the phosphorylation of STAT3 tyrosine 705 (Tyr-705) and had slight effects on STAT1 and STAT5 phosphorylation. Tyrosine signal transducer and activator of transcription 3 Homo sapiens