Pub. Date : 2017
PMID : 31966418
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TGF-beta1 gene silencing can enhances the sensitivity of breast cancer to cisplatin partially by restraining the occurrence of EMT. | Cisplatin | transforming growth factor beta 1 | Homo sapiens |
| 2 | This study aims to investigate the effect of TGF-beta1 on cisplatin (DDP) inhibiting the proliferation, migration and invasion of breast cancer and its correlation with EMT. | Cisplatin | transforming growth factor beta 1 | Homo sapiens |
| 3 | The inhibitory activity of cisplatin on cell proliferation, migration and invasion of breast cancer were significantly enhanced after TGF-beta1 siRNA transfection (P<0.05). | Cisplatin | transforming growth factor beta 1 | Homo sapiens |
| 4 | Therefore, we concluded that TGF-beta1 gene silencing can enhance the sensitivity of breast cancer to cisplatin on proliferation, migration and invasion partially by restraining the occurrence of EMT. | Cisplatin | transforming growth factor beta 1 | Homo sapiens |