Title : Antibiotic Degradation by Commensal Microbes Shields Pathogens.

Pub. Date : 2020 Mar 23

PMID : 31964746






2 Functional Relationships(s)
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1 The complex bacterial populations that constitute the gut microbiota can harbor antibiotic-resistance genes (ARGs), including those encoding for beta-lactamase enzymes (BLA), which degrade commonly prescribed antibiotics such as ampicillin. Ampicillin beta-lactamase Escherichia coli
2 Production of functional BLA by commensal E. coli markedly reduced clearance of these pathogens and enhanced systemic dissemination during ampicillin treatment. Ampicillin beta-lactamase Escherichia coli