Title : 14-3-3 protein binding blocks the dimerization interface of caspase-2.

Pub. Date : 2020 Aug

PMID : 31961068






1 Functional Relationships(s)
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1 Here, we report the structural characterization of the complex between proC2 and 14-3-3 by hydrogen/deuterium mass spectrometry (HDX-MS) and protein crystallography to determine the molecular basis for 14-3-3-mediated inhibition of C2 activation. Hydrogen caspase 2 Homo sapiens