Title : Randomized trial of 3-drug combination for lumbar nerve root epidural injections with a TNF-α inhibitor in treatment of lumbar stenosis.

Pub. Date : 2020 Apr

PMID : 31955619






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1 Background: This study was to assess the clinical efficacy of epidural injections with tumor necrosis factor-alpha (TNF-alpha) inhibitor in patients with chronic radicular pain caused by lumbar spinal stenosis (LSS).Methods: In a randomized controlled trial (RCT), patients diagnosed with mild-to-moderate LSS underwent epidural intervention with three different drugs and were allocated to TNF-alpha inhibitor group (Group A), steroid group (Group B) and lidocaine-only group (Group C). Steroids tumor necrosis factor Homo sapiens