Title : Low-dose Btk inhibitors selectively block platelet activation by CLEC-2.

Pub. Date : 2021 Jan 1

PMID : 31949019






1 Functional Relationships(s)
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1 In this study we show that low concentrations of the Btk inhibitor ibrutinib block CLEC-2-mediated activation and tyrosine phosphorylation including Syk and PLCgamma2 in human platelets. ibrutinib phospholipase C gamma 2 Homo sapiens