Title : Decreased sphingolipid synthesis in children with 17q21 asthma-risk genotypes.

Pub. Date : 2020 Feb 3

PMID : 31929190






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 ORMDL3 inhibits sphingolipid de novo synthesis. Sphingolipids ORMDL sphingolipid biosynthesis regulator 3 Homo sapiens
2 These findings connect genetic 17q21 variations that are associated with asthma risk and higher ORMDL3 expression to lower sphingolipid synthesis in humans. Sphingolipids ORMDL sphingolipid biosynthesis regulator 3 Homo sapiens