Title : Diverse Gene Expressions in the Prediction of Cuprizone-Induced Demyelination.

Pub. Date : 2020 Mar

PMID : 31916130






1 Functional Relationships(s)
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1 Our results demonstrated that CPZ-induced demyelination induces apparent alterations in the expression of most of the myelin-related genes, including the 6 key genes MBP, MAG, and MOG and GFAP, CXCR4, and NgR, which were observed to be downregulated and upregulated, respectively, suggesting that the differences in gene expression in vivo could serve as potential therapeutic targets for remyelination. Cuprizone myelin basic protein Mus musculus