Pub. Date : 2020 Aug
PMID : 31902946
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ACTN4 rs62121818, MYH9 rs2239781, CYP3A5*3, and age explained 20.5% interindividual variability of tacrolimus concentration in the total cohort. | Tacrolimus | actinin alpha 4 | Homo sapiens |
| 2 | In CYP3A5 nonexpressers, ACTN4 rs62121818 and MYH9 rs2239781 together explained 14.6% variation of tacrolimus C0/D. | Tacrolimus | actinin alpha 4 | Homo sapiens |
| 3 | Podocyte-associated gene polymorphisms, especially ACTN4 rs62121818 and MYH9 rs2239781, were the other most important biomarkers for tacrolimus whole blood levels. | Tacrolimus | actinin alpha 4 | Homo sapiens |