Title : DDIAS promotes STAT3 activation by preventing STAT3 recruitment to PTPRM in lung cancer cells.

Pub. Date : 2020 Jan 2

PMID : 31900385






4 Functional Relationships(s)
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1 We showed that DDIAS promotes tyrosine phosphorylation of signal transducer and activator of transcription 3 (STAT3), which is constitutively activated in malignant cancers. Tyrosine signal transducer and activator of transcription 3 Homo sapiens
2 We showed that DDIAS promotes tyrosine phosphorylation of signal transducer and activator of transcription 3 (STAT3), which is constitutively activated in malignant cancers. Tyrosine signal transducer and activator of transcription 3 Homo sapiens
3 Interestingly, siRNA protein tyrosine phosphatase (PTP) library screening revealed protein tyrosine phosphatase receptor mu (PTPRM) as a novel STAT3 PTP. Tyrosine signal transducer and activator of transcription 3 Homo sapiens
4 Interestingly, siRNA protein tyrosine phosphatase (PTP) library screening revealed protein tyrosine phosphatase receptor mu (PTPRM) as a novel STAT3 PTP. Tyrosine signal transducer and activator of transcription 3 Homo sapiens