Pub. Date : 2020 Feb
PMID : 31894313
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin alleviates endometrial hyperplasia through the UCA1/miR-144/TGF-beta1/AKT signaling pathway. | Metformin | microRNA 144 | Homo sapiens |
| 2 | By contrast, Met reduced cell viability, promoted cell apoptosis, and reduced the expression levels of UCA1, TGF-beta and p-AKT, while upregulating the expression of miR-144 and active Caspase-3 in a dose-dependent manner. | Metformin | microRNA 144 | Homo sapiens |
| 3 | In conclusion, the current study suggested that Met reduces the risk of EH by reducing the expression levels of UCA1, TGF-beta and p-AKT, while increasing the levels of miR-144 and active Caspase-3 in a dose-dependent manner. | Metformin | microRNA 144 | Homo sapiens |