Title : The behavior of asialotransferrin-iron in the rat.

Pub. Date : 1988 Dec

PMID : 3189316






1 Functional Relationships(s)
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1 This study 1) confirmed that asialotransferrin-iron uptake by the hepatocyte is mediated by both transferrin and asialoglycoprotein receptors; 2) demonstrated that not only asialotransferrin but also transferrin of low sialic acid content will increase iron turnover and lead to excessive iron loading of the hepatocyte; 3) and showed that the intrahepatocyte metabolism of asialotransferrin-iron did not differ from that of iron delivered by normal transferrin. N-Acetylneuraminic Acid transferrin Homo sapiens