Title : Nafamostat and sepimostat identified as novel neuroprotective agents via NR2B N-methyl-D-aspartate receptor antagonism using a rat retinal excitotoxicity model.

Pub. Date : 2019 Dec 31

PMID : 31892740






2 Functional Relationships(s)
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1 The neuroprotective effects of nafamostat and the NR2B antagonist ifenprodil were remarkably suppressed by spermidine, a naturally occurring polyamine that modulates the NR2B subunit. Spermidine glutamate ionotropic receptor NMDA type subunit 2B Rattus norvegicus
2 The neuroprotective effects of nafamostat and the NR2B antagonist ifenprodil were remarkably suppressed by spermidine, a naturally occurring polyamine that modulates the NR2B subunit. Spermidine glutamate ionotropic receptor NMDA type subunit 2B Rattus norvegicus