Title : Acrolein-induced apoptosis of smooth muscle cells through NEAT1-Bmal1/Clock pathway and a protection from asparagus extract.

Pub. Date : 2020 Mar

PMID : 31864078






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Acrolein-induced apoptosis of smooth muscle cells through NEAT1-Bmal1/Clock pathway and a protection from asparagus extract. Acrolein nuclear paraspeckle assembly transcript 1 Homo sapiens
2 However, whether acrolein, an environmental pollutant, affects the apoptosis of VSMCs by regulating NEAT1 and clock genes is still elusive. Acrolein nuclear paraspeckle assembly transcript 1 Homo sapiens
3 Expression of NEAT1, Bmal1 and Clock was decreased by acrolein, while was ameliorated by AE. Acrolein nuclear paraspeckle assembly transcript 1 Homo sapiens
4 In this study, we demonstrated that VSMCs apoptosis induced by acrolein was associated with downregulation of NEAT1 and Bmal1/Clock. Acrolein nuclear paraspeckle assembly transcript 1 Homo sapiens