Pub. Date : 2020 Jan
PMID : 31853327
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dexamethasone and lenvatinib inhibit migration and invasion of non-small cell lung cancer by regulating EKR/AKT and VEGF signal pathways. | Dexamethasone | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Notably, the results demonstrated that dexamethasone eradicated the promotion effects of TGF-beta1 on the AKT/epithelial-mesenchymal transition process and lenvatinib extinguished tumor cell metastasis by targeting VEGF. | Dexamethasone | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | In conclusion, dexamethasone inhibited AKT/ERK phosphorylation and lenvatinib antagonism bound VEGF leading to the limitation of migration and invasion of cancer cells in NSCLC. | Dexamethasone | AKT serine/threonine kinase 1 | Homo sapiens |