Title : Hormonal status affects plasma exposure of tamoxifen and its main metabolites in tamoxifen-treated breast cancer patients.

Pub. Date : 2019 Dec 19

PMID : 31852530






1 Functional Relationships(s)
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1 BACKGROUND: Tamoxifen is considered a prodrug of its active metabolite endoxifen, which is dependent on the CYP2D6 and CYP3A enzymes. Tamoxifen cytochrome P450 family 2 subfamily D member 6 Homo sapiens