Title : Ursolic Acid Treatment Alleviates Diabetic Kidney Injury By Regulating The ARAP1/AT1R Signaling Pathway.

Pub. Date : 2019

PMID : 31849504






2 Functional Relationships(s)
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1 Histochemical analysis results showed significantly lower expression levels of ARAP1, AT1R, FN, NOX2, 8-OHdG, IL-1beta and IL-18 in renal tissues in the UA treatment group than in the DN group. ursolic acid interleukin 1 beta Mus musculus
2 Western blotting and RT-qPCR data also revealed UA-induced decreases in the renal levels of the ARAP1, AT1, NOX4, NOX2, TGF-beta1, FN, collagen IV, IL-1beta and IL-18 proteins in vivo and/or in vitro (p<0.01). ursolic acid interleukin 1 beta Mus musculus