Pub. Date : 2020 Feb 3
PMID : 31845908
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models. | Ivermectin | heat shock protein family B (small) member 1 | Homo sapiens |
| 2 | Ivermectin directly binds this pocket to inhibit MAPKAP2-mediated HSP27 phosphorylation and depolymerization, thereby blocking HSP27-regulated survival signaling and client-oncoprotein interactions. | Ivermectin | heat shock protein family B (small) member 1 | Homo sapiens |
| 3 | Ivermectin directly binds this pocket to inhibit MAPKAP2-mediated HSP27 phosphorylation and depolymerization, thereby blocking HSP27-regulated survival signaling and client-oncoprotein interactions. | Ivermectin | heat shock protein family B (small) member 1 | Homo sapiens |