Title : Nerve Growth Factor Protects Against Pyrethroid-Induced Endoplasmic Reticulum (ER) Stress in Primary Hippocampal Neurons.

Pub. Date : 2020 Mar 1

PMID : 31841155






2 Functional Relationships(s)
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1 Furthermore, deltamethrin decreased Akt (Protein kinase B) phosphorylation, which was significantly prevented by co-treatment with NGF or SC-79 in cells. decamethrin thymoma viral proto-oncogene 1 Mus musculus
2 Collectively, these results demonstrate that the loss of NGF following ER stress may contribute to deltamethrin-induced apoptosis in the hippocampus through the Akt signaling pathway, and that this may provide a plausible mechanism for impaired learning and memory observed following exposure of mice to deltamethrin. decamethrin thymoma viral proto-oncogene 1 Mus musculus