Title : Targeted regulation of fibroblast state by CRISPR-mediated CEBPA expression.

Pub. Date : 2019 Dec 11

PMID : 31829168






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CEBPA over-expression by transient transfection in IPF-derived fibroblasts significantly reduced pro-fibrotic gene expression, ECM deposition and alphaSMA expression and promoted the formation of lipid droplets measured by Oil Red O staining and increased lipofibroblast gene expression. oil red O CCAAT enhancer binding protein alpha Homo sapiens