Title : The Antimalarial Chloroquine Reduces the Burden of Persistent Atrial Fibrillation.

Pub. Date : 2019

PMID : 31827438






1 Functional Relationships(s)
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1 We used patch clamp to determine the IC50 of IK1 and IKACh block by chloroquine and molecular modeling to simulate the interaction between chloroquine and Kir2.1 and Kir3.1, the molecular correlates of IK1 and IKACh. Chloroquine potassium inwardly rectifying channel subfamily J member 2 Homo sapiens