Title : Approaches to Tumor Classification in Pulmonary Sarcomatoid Carcinoma.

Pub. Date : 2019

PMID : 31824199






1 Functional Relationships(s)
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1 Although rare, PSC has increased their interest among oncologist community for different reasons: a. identification of the epithelial-to-mesenchymal phenomenon as a major mechanism of secondary resistance to tyrosine kinase inhibitors; b. over-expression of PD-L1 and effective treatment with immunotherapy; c. identification of c-MET exon 14 skipping mutation representing an effective target to crizotinib and other specific inhibitors. crizotinib CD274 molecule Homo sapiens