Title : Human UDP-galactose 4'-epimerase (GALE) is required for cell-surface glycome structure and function.

Pub. Date : 2020 Jan 31

PMID : 31819007






1 Functional Relationships(s)
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1 Using immunoblotting, flow cytometry, and LC-MS-based glycolipid and glycan profiling, we found that CRISPR/Cas9-mediated GALE deletion in human cells triggers major imbalances in NSs and dramatic changes in glycolipids and glycoproteins, including a subset of integrins and the cell-surface death receptor FS-7-associated surface antigen. Glycolipids UDP-galactose-4-epimerase Homo sapiens