Title : Results of a phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA-defective tumours.

Pub. Date : 2020 Feb

PMID : 31813938






1 Functional Relationships(s)
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1 BACKGROUND: Tumour cells with BRCA1/2 gene mutations demonstrate increased sensitivity to platinum and poly (ADP-ribose) polymerase (PARP) inhibitors. Platinum BRCA1 DNA repair associated Homo sapiens