Title : A TGF-β-MTA1-SOX4-EZH2 signaling axis drives epithelial-mesenchymal transition in tumor metastasis.

Pub. Date : 2020 Mar

PMID : 31811272






1 Functional Relationships(s)
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1 The histone methyltransferase EZH2, a component of the polycomb (PcG) repressive complex 2 (PRC2), was identified as a critical responsive gene of the TGF-beta-MTA1-SOX4 signaling in three different epithelial cancer cell lines, suggesting that this signaling acts broadly in cancer cells in vitro. phthalocyanine transforming growth factor beta 1 Homo sapiens