Title : Preclinical Evaluation of Ureidosulfamate Carbonic Anhydrase IX/XII Inhibitors in the Treatment of Cancers.

Pub. Date : 2019 Dec 2

PMID : 31810330






2 Functional Relationships(s)
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1 The elucidation of the crystal structure of the catalytic domains of CAIX/XII provided the basis for the generation of CAIX/XII selective inhibitors based on the sulfonamide, sulfamate and coumarins chemical structures. Sulfonamides carbonic anhydrase 9 Homo sapiens
2 The elucidation of the crystal structure of the catalytic domains of CAIX/XII provided the basis for the generation of CAIX/XII selective inhibitors based on the sulfonamide, sulfamate and coumarins chemical structures. Sulfonamides carbonic anhydrase 9 Homo sapiens