Title : PSA-NCAM Colocalized with Cholecystokinin-Expressing Cells in the Hippocampus Is Involved in Mediating Antidepressant Efficacy.

Pub. Date : 2020 Jan 22

PMID : 31801810






3 Functional Relationships(s)
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1 Pharmacological digestion of PSA-NCAM impaired the efficacy of antidepressant fluoxetine (FLX), a selective serotonin reuptake inhibitor, but not the efficacy of benzodiazepine anxiolytic diazepam. Fluoxetine neural cell adhesion molecule 1 Mus musculus
2 Pharmacological digestion of PSA-NCAM impaired the efficacy of antidepressant fluoxetine (FLX), a selective serotonin reuptake inhibitor, but not the efficacy of benzodiazepine anxiolytic diazepam. Fluoxetine neural cell adhesion molecule 1 Mus musculus
3 Interestingly, the FLX-induced elevation of expression of p11, but not mature BDNF, was impaired by the digestion of PSA-NCAM. Fluoxetine neural cell adhesion molecule 1 Mus musculus