Title : Substitution of Arginine 120 in Human D-Amino Acid Oxidase Favors FAD-Binding and Nuclear Mistargeting.

Pub. Date : 2019

PMID : 31799256






1 Functional Relationships(s)
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1 Here, we focused on arginine 120, a residue located at the protein interface, 20 A from the assumed second ligand-binding site, showing a different orientation of the side chain in the hDAAO-benzoate complex, and corresponding to Ser119 in rat DAAO, which is part of a putative nuclear translocation signal (NTS). Benzoates D-amino-acid oxidase Rattus norvegicus