Title : Translation of peptidoglycan metabolites into immunotherapeutics.

Pub. Date : 2019

PMID : 31798878






1 Functional Relationships(s)
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1 In this review, we summarise the discovery of two key peptidoglycan metabolites, gamma-d-glutamyl-meso-diaminopimelic acid (iE-DAP) and muramyl dipeptide and their respective receptors, Nod1 and Nod2, and review progress towards translating these findings into therapeutic agents. N(2)-(gamma-D-glutamyl)-meso-2,2'-diaminopimelic acid death associated protein Homo sapiens